Annotation Overview for fig|272557.1.peg.587 in Aeropyrum pernix K1:
Glucose-6-phosphate isomerase, archaeal II (EC 5.3.1.9) / Mannose-6-phosphate isomerase, archaeal (EC 5.3.1.8)
| current assignment |
| |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| taxonomy id | 272557 | contig | ||||||||
| internal links | genome browser | feature evidence | sequence | ACH [?] | show essentially identical genes | |||||||
| PubMed links | 14551194 | |||||||||
| annotation history | run tool | |||||||||
| data base cross references (dbxref) | ||||||||||
This feature is part of a subsystem
Reasons for Current Assignment
The encoded protein plays multiple roles which are implemented by distinct domains within the
feature. The roles are "Glucose-6-phosphate isomerase, archaeal II (EC 5.3.1.9)" and
"Mannose-6-phosphate isomerase, archaeal (EC 5.3.1.8)". The protein occurs in 2 subsystems:
"Formaldehyde assimilation: Ribulose monophosphate pathway", and "Glycolysis and Gluconeogenesis,
including Archaeal enzymes". In "Formaldehyde assimilation: Ribulose monophosphate pathway", it
appears to play a functional role that we have not associated with any other gene. In "Glycolysis
and Gluconeogenesis, including Archaeal enzymes", it appears to play a functional role that we have
not associated with any other gene. The function of this gene is asserted in 14551194.
The function of genes having the same functional roles have been described in Thermoplasma
acidophilum (14551194) and Pyrobaculum aerophilum (15252053, 15290326). These are homologous proteins which implement the same function.
Compare Regions
The chromosomal region of the focus gene (top) is compared with four similar organisms. The graphic is centered on the focus gene, which is red and numbered 1. Sets of genes with similar sequence are grouped with the same number and color. Genes whose relative position is conserved in at least four other species are functionally coupled and share gray background boxes. The size of the region and the number of genomes may be reset. Click on any arrow in the display to refocus the comparison on that gene. The focus gene always points to the right, even if it is located on the minus strand.
